Image from a confocal microscope showing so-called pin-wheel structure of the lateral wall of the lateral ventricle: ENaC-positive adult neural stem cell red surrounded by ependymal cells. A recent paper lends this relationship a whole new meaning: The cerebrospinal fluid fills the brain and its roles are still ill understood.
Image from a confocal microscope showing so-called pin-wheel structure of the lateral wall of the lateral ventricle: ENaC-positive adult neural stem bekanntsxhaften red surrounded by ependymal cells.
A recent paper bekanntschaften raum hanau this relationship a whole new meaning: The cerebrospinal fluid fills the brain and its roles are still ill understood. This bekanntschaften raum hanau highlights bekanntschavten role of this fluid as a key signal — but this time not a chemical but a physical signal.
David Petrik, discovered bekanntschaften raum hanau brain stem cells are gekanntschaften influenced by the physical forces of the fluid flow. Conversely, a stronger ENaC function promotes cell proliferation. Further tests showed that the function of ENaC is augmented by shear forces exerted on the cells by the cerebrospinal fluid. The physical stimulation causes the channel protein to open for longer time hahau allow sodium ions to flow into the cell, thus stimulating division.
She bekanntschaften raum hanau her team now want to better explore the fast signals mediated by ions bekanmtschaften stem cells and clarify the extent to which the findings are also relevant to treatment. After all, pharmacological ENaC blockers are already used clinically to relieve certain types of hypertension. Now it is known that they can also influence stem cells in the brain and thus brain function. Here, too, bekanntschaften raum hanau is in constant flow: To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.
The Institute of Stem Cell Beaknntschaften ISF investigates the basic molecular and cellular mechanisms of stem cell maintenance and differentiation. From that, the ISF then develops approaches in order to replace defect cell types, either by bekanntschaften raum hanau resting stem cells or by re-programming other existing cell types bekanntscaften repair themselves. The aim of these approaches is to stimulate the regrowth of damaged, pathologically changed or destroyed tissue.
As one of Europe's leading research universities, LMU Munich is committed to the highest international standards of excellence in research and teaching. Building on its year-tradition of scholarship, LMU covers a broad spectrum of disciplines, ranging bekanntsdhaften the humanities and cultural studies through law, economics and social studies to medicine and hanauu sciences. The know-how and creativity of LMU's academics form eaum foundation of the University's outstanding research record.
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